|Description:||The MDQ is a brief, self-rated questionnaire that can be used to screen patients at risk for bipolar disorder.|
|Disease States:||Bipolar disorder|
|Time to administer:||< 5 minutes|
|Commonly used in:||Clinical Practice|
|Detailed Description:||The MDQ is a screening instrument for bipolar disorder that can be administered quickly and easily in primary care settings.2,3 The MDQ is comprised of 13 symptom-specific questions and two additional items assessing co-occurrence of symptoms and functional impairment.1,3 If a patient has a positive screening on the MDQ, the healthcare provider should initiate a comprehensive medical evaluation for bipolar disorder.2,3
A positive screen requires the following criteria be met1,3:
|Scale Validity:||Sensitivity and specificity of the MDQ depends on the population examined. In an outpatient clinic targeting a mood disorder population, the MDQ demonstrated 73% sensitivity and 90% specificity.1,3 In the general population, the MDQ demonstrated 28% sensitivity and 97% specificity.3|
|Alternative Versions:||The MDQ has an adolescent version called the MDQ-A.6 The MDQ-A has both self-report and parent-report versions, with the parent-report version reportedly more useful in detecting possible bipolar disorder.6 The parent-report version (P-MDQ) can also be used in younger pediatric populations.7|
|Cited Limitations:||The MDQ is best at screening for bipolar I disorder (depression and mania) and is not as sensitive to bipolar II disorder (depression and hypomania) or other forms of bipolar disorder (bipolar disorder not otherwise specified).8|
Supporting references for the filters are as follows:
Disease State: Bipolar disorder1-3; Validated Uses: Screening1-4; Populations: Adult1,5; Administration Method: Self-report1-3; Time to administer: < 5 minutes3,5; Commonly used in: Clinical Practice1-3
- Hirschfeld, RM et al. Am J Psychiatry. 2000;157(11):1873-1875.
- Hirschfeld, RM. Prim Care Companion J Clin Psychiatry. 2002;4(1):9-11.
- STABLE National Coordination Council. Standards for bipolar excellence resource toolkit. 2015.
- Rush, AJ et al. Handbook of Psychiatric Measures. (American Psychiatric Publishing, Inc., 2008).
- Williams, N. Occup Med (Lond). 2017;67(2):165-166.9.
- Wagner, KD et al. J Clin Psychiatry. 2006;67(5):827-830.
- Youngstrom, E et al. Bipolar Disord. 2005;7(6):507-517.
- Miller, C. Journal of Affective Disorders. 2004;81(2):167-171.