
Clinical Article Summary
Adjunctive Antidepressant Use and Symptomatic Recovery Among Bipolar Depressed Patients with Concomitant Manic Symptoms: Findings From the STEP-BD Study
Goldberg et al evaluated patients from the naturalistic treatment assignment of the STEP-BD study to determine whether antidepressant medications are effective in treating patients with bipolar depression with subsyndromal manic features.

Clinical Article Summary
Thresholds for Severity, Remission and Recovery Using the Functioning Assessment Short Test (FAST) in Bipolar Disorder
Bonnin et al. (2018) aimed to define severity cutoffs on the Functional Assessment Short Test (FAST) to classify functional impairment more accurately in patients with bipolar disorders and inform the efficacy of pharmacologic and psychological treatments in randomized controlled trials.

Clinical Article Summary
Clinical Correlates of DSM-5 Mixed Features in Bipolar Disorder: A Meta-Analysis
Bartoli et al (2020) looked at clinical characteristics of patients with bipolar disorder with mixed features and identified correlates that appear to be distinct in people with manic/hypomanic index episodes.

Clinical Article Summary
Unrecognized Bipolar Disorder in Patients With Depression Managed in Primary Care: A Systematic Review and Meta-Analysis
Daveney, et al explore the characteristics of patients with mixed symptoms, as compared to those without mixed symptoms, in both bipolar disorder and major depressive disorder.