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Clinical Article Summaries

Clinical Article Summaries

Read our summaries of timely clinical research to help you stay current with information affecting your day-to-day practice.

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The Rapid Mood Screener (RMS): A Novel and Pragmatic Screener for Bipolar I Disorder

Clinical Article

The Rapid Mood Screener (RMS): A Novel and Pragmatic Screener for Bipolar I Disorder

McIntyre et al developed a simple 6-question Rapid Mood Screener (RMS) to screen for manic symptoms and features of bipolar I disorder.

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Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

Clinical Article Summary

Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial was a 7-year nationwide clinical trial designed to evaluate the efficacy of different medications in patients who did not respond to an initial antidepressant. Rush et al. (2006) evaluated acute and long-term treatment outcomes in patients who participated in the STAR*D trial and identified differences in response and remission rates and time to remission across patients who received up to four sequential treatment steps.
The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Study and Its Implications for Patients With Chronic Schizophrenia

Clinical Article Summary

The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Study and Its Implications for Patients With Chronic Schizophrenia

Lieberman et al reported efficacy and tolerability results from the first phase of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study, which compared first- generation antipsychotic medication with second-generation antipsychotic medication in people with schizophrenia. McEvoy et al and Stroup et al then reported efficacy and tolerability results from the second phase of CATIE, which compared responses to subsequent therapy with a different second-generation antipsychotic in people with schizophrenia who discontinued their previous second-generation antipsychotic.
The Rapid Mood Screener (RMS): A Novel and Pragmatic Screener for Bipolar I Disorder

Clinical Article Summary

The Rapid Mood Screener (RMS): A Novel and Pragmatic Screener for Bipolar I Disorder

McIntyre et al developed a simple 6-question Rapid Mood Screener (RMS) to screen for manic symptoms and features of bipolar I disorder.
Clinician Descriptions of Communication Strategies to Improve Treatment Engagement by Racial/Ethnic Minorities in Mental Health Services: A Systematic Review

Clinical Article Summary

Clinician Descriptions of Communication Strategies to Improve Treatment Engagement by Racial/Ethnic Minorities in Mental Health Services: A Systematic Review

Aggarwal et al. (2016) conducted a systematic literature review to identify patient-clinician communication factors that could account for low mental health treatment engagement rates among patients of racial/ethnic minority status.
Adjunctive Antidepressant Use and Symptomatic Recovery Among Bipolar Depressed Patients with Concomitant Manic Symptoms: Findings From the STEP-BD Study

Clinical Article Summary

Adjunctive Antidepressant Use and Symptomatic Recovery Among Bipolar Depressed Patients with Concomitant Manic Symptoms: Findings From the STEP-BD Study

Goldberg et al evaluated patients from the naturalistic treatment assignment of the STEP-BD study to determine whether antidepressant medications are effective in treating patients with bipolar depression with subsyndromal manic features.
Thresholds for Severity, Remission and Recovery Using the Functioning Assessment Short Test (FAST) in Bipolar Disorder

Clinical Article Summary

Thresholds for Severity, Remission and Recovery Using the Functioning Assessment Short Test (FAST) in Bipolar Disorder

Bonnin et al. (2018) aimed to define severity cutoffs on the Functional Assessment Short Test (FAST) to classify functional impairment more accurately in patients with bipolar disorders and inform the efficacy of pharmacologic and psychological treatments in randomized controlled trials.
Clinical Correlates of DSM-5 Mixed Features in Bipolar Disorder: A Meta-Analysis

Clinical Article Summary

Clinical Correlates of DSM-5 Mixed Features in Bipolar Disorder: A Meta-Analysis

Bartoli et al (2020) looked at clinical characteristics of patients with bipolar disorder with mixed features and identified correlates that appear to be distinct in people with manic/hypomanic index episodes.
Characteristics of Patients with Early Bipolar Disorder

Clinical Article Summary

Characteristics of Patients with Early Bipolar Disorder

O Donovan, et al identify characteristics of patients who experience depression before bipolar disorder.

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