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For US Nurse Practitioners

Welcome to NP Psych Navigator, a curated library of clinical tools, educational resources, and inspiring stories from your peers. Our mission is to support your needs as you support your patients with mental illness. 

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Learn more about NP Psych Navigator and our mission to help nurse practitioners improve mental healthcare.

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Fundamentals of Psychopharmacology

Psychiatry Fundamentals

Fundamentals of Psychopharmacology

Understanding psychopharmacology is foundational to providing mental healthcare. Review pathways, brain regions, receptors, and functions associated with various neurotransmitters that are thought to play a role in psychiatry.
Dopamine and Serotonin Psychopharmacology Video

Clinical Insight

Dopamine and Serotonin Psychopharmacology Video

Dopamine and serotonin are neurotransmitters that are thought to regulate mood, behavior, and cognition, and their dysregulation may be associated with various psychiatric conditions. This video aims to help healthcare providers better understand the roles dopamine and serotonin may play in psychiatry.
Evolution of Antipsychotics Podcast

Peer Exchange

Evolution of Antipsychotics Podcast

Pradeep Manudhane, MD, and "Tony" Amberg, MSN, APRN, PMHNP-BC, explore the history and evolution of antipsychotics, tracing their origins from the 1950s to their modern applications in treating mental health disorders including schizophrenia.
Patient Case Navigator: Differentiating Bipolar I Disorder From Major Depressive Disorder

Interactive Case Study

Patient Case Navigator: Differentiating Bipolar I Disorder From Major Depressive Disorder

Welcome to the Patient Case Navigator, an interactive learning experience for Nurse Practitioners. Please use the Next or Previous buttons at the bottom of the page to move forward or backwards.

Recommended on NP Psych Navigator

Anhedonia and Cognitive Function in Adults With MDD: Results From the International Mood Disorders Collaborative Project

Clinical Article

Anhedonia and Cognitive Function in Adults With MDD: Results From the International Mood Disorders Collaborative Project

The International Mood Disorders Collaborative Project found a significant correlation between anhedonia and self-reported cognitive impairment in adults with major depressive disorder (MDD), which may help to identify individuals with MDD who are at higher risk of cognitive decline over time.
Fundamentals of Major Depressive Disorder

Disease Primer

Fundamentals of Major Depressive Disorder

Major depressive disorder (MDD) is one of the most recognized mental disorders in the United States. Learn more about the prevalence, pathophysiology, diagnosis, and management of MDD here.
State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder

Clinical Article

State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder

Rive et al use functional MRI to look at some of the differences between patients with bipolar depression and major depressive disorder.
Unrecognized Bipolar Disorder in Patients With Depression Managed in Primary Care: A Systematic Review and Meta-Analysis

Clinical Article

Unrecognized Bipolar Disorder in Patients With Depression Managed in Primary Care: A Systematic Review and Meta-Analysis

Daveney et al explore the characteristics of patients with mixed symptoms, as compared to those without mixed symptoms, in both bipolar disorder and major depressive disorder.

NP Perspectives

When it comes to giving the best care to your patients, experience matters. Check out our Clinical Insights to hear from our vibrant community of nurse practitioners.

NP Spotlight: Kathleen T. McCoy, DNSc, APRN, PMHNP-BC, PMHCNS-BC, FNP-BC, FAANP
NP Spotlight: Kathleen T. McCoy, DNSc, APRN, PMHNP-BC, PMHCNS-BC, FNP-BC, FAANP
NP Spotlight: Chris Lambert, FNP-C, DNP
NP Spotlight: Chris Lambert, FNP-C, DNP
NP Spotlight: Jeremy Schreiber, MSN, PMHNP-BC
NP Spotlight: Jeremy Schreiber, MSN, PMHNP-BC
NP Spotlight: Katherine Sullivan, MSN, APN
NP Spotlight: Katherine Sullivan, MSN, APN


Clinical Tools

Understanding Affective Switch in Bipolar I Disorder

Quick Guide for Providers

Understanding Affective Switch in Bipolar I Disorder

Patients with bipolar I disorder (BP-1) may experience affective switch, which is a sudden transition in mood episodes between mania and depression. Affective switch can be triggered by certain medications as well as social or environmental factors. Learn how to recognize and monitor for signs of affective switch in patients with BP-1.
Number Needed to Treat (NNT) and Number Needed to Harm (NNH) in Psychiatry

Quick Guide for Providers

Number Needed to Treat (NNT) and Number Needed to Harm (NNH) in Psychiatry

Number needed to treat (NNT) and number needed to harm (NNH) are metrics that can be used to evaluate the clinical relevance of findings from clinical trials. Together, NNT and NNH can be used to express the likelihood of being helped or harmed (LHH), which may be helpful for communicating and understanding the potential benefits and risks of a treatment. This quick guide will review the definitions, calculations, and interpretations of NNT, NNH, and LHH. For additional information, please visit our Clinical Insights section for a video featuring Dr Leslie Citrome on this topic.
Mixed Features in Bipolar I Disorder

Quick Guide for Providers

Mixed Features in Bipolar I Disorder

Many patients with bipolar I disorder (BP-1) can experience mixed features, which is the simultaneous occurrence of depressive and manic symptoms. Mixed features can be associated with negative outcomes. Therefore, it is important for healthcare providers to evaluate BP-1 patients for the presence of mixed features to provide appropriate management strategies.
Partial Response to Antidepressant Therapy and Residual Symptoms of Major Depressive Disorder (MDD)

Educate Your Patient

Partial Response to Antidepressant Therapy and Residual Symptoms of Major Depressive Disorder (MDD)

Some patients with major depressive disorder (MDD) may experience lingering symptoms of depression, known as residual symptoms, with their initial antidepressant therapy. This patient resource provides MDD patients with information on what residual symptoms are, why they may experience them, how to recognize and monitor them, and how their healthcare providers can help manage them.

Clinical Education

Predictors of Treatment-Emergent Affective Switch Quiz

Test Your Knowledge

Predictors of Treatment-Emergent Affective Switch Quiz

Affective switch is a phenomenon that can occur in bipolar I disorder. In particular, affective switch can be triggered by certain medications in what is known as a treatment-emergent affective switch (TEAS), as well as by social and environmental factors. Test your knowledge of the potential symptoms and triggers of affective switch, including TEAS.
Anhedonia and Cognitive Function in Adults With MDD: Results From the International Mood Disorders Collaborative Project

Clinical Article Summary

Anhedonia and Cognitive Function in Adults With MDD: Results From the International Mood Disorders Collaborative Project

The International Mood Disorders Collaborative Project found a significant correlation between anhedonia and self-reported cognitive impairment in adults with major depressive disorder (MDD), which may help to identify individuals with MDD who are at higher risk of cognitive decline over time.
Self-Reported History of Manic/Hypomanic Switch Associated With Antidepressant Use: Data From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

Clinical Article Summary

Self-Reported History of Manic/Hypomanic Switch Associated With Antidepressant Use: Data From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

The Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study investigated treatment-emergent risk factors associated with manic and hypomanic episodes in patients with bipolar disorder. The results of this study provide insights into the prevalence of manic/hypomanic switch in patients undergoing antidepressant therapy and may help guide decisions on appropriate management.
Patient Case Quiz: Using the Rapid Mood Screener in Practice

Test Your Knowledge

Patient Case Quiz: Using the Rapid Mood Screener in Practice

What is the appropriate patient type for the Rapid Mood Screener? Review this patient case to test your knowledge.

Psychiatry Fundamentals 

Psychiatry draws upon skills that are essential to the nurse practitioner approach to patient care, empathy, compassion, and understanding. A thorough knowledge of the different mental illnesses complements those skills.

Learn more about Psychiatry Fundamentals
Psychiatry Fundamentals 

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