Major Depressive Disorder (MDD) is a prevalent, disabling, and chronic condition. Identifying patients who have not responded to a course of adequate treatment is important as these patients may benefit from adjunctive pharmacotherapy or psychotherapy.
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Unrecognized Bipolar Disorder in Patients With Depression Managed in Primary Care: A Systematic Review and Meta-Analysis
Daveney et al explore the characteristics of patients with mixed symptoms, as compared to those without mixed symptoms, in both bipolar disorder and major depressive disorder.